Temple University - of the Commonwealth System of Higher Education
发明人:
Kamel Khalili
申请号:
US15559902
公开号:
US20180073019A1
申请日:
2016.03.18
申请国别(地区):
US
年份:
2018
代理人:
摘要:
Compositions and methods are provided for Tat-inducible expression of a CRISPR-associated endonuclease by a truncated HIV LTR promoter containing at least a core region and a TAR region of a HIV LTR promoter. The compositions may be used as a therapeutic treatment for the treatment and/or prevention of HIV.