Peng Li,Hailin Zheng,Jun Zhao,Lawrence P. Wennogle
申请号：
US15502144
公开号：
US10131671B2
申请日:
2015.08.07
申请国别(地区):
US
年份:
2018
代理人:
摘要：
The invention relates to novel inhibitors of phosphodiesterase 1 (PDE1), useful for the treatment of diseases or disorders characterized by disruption of or damage to certain cGMP/PKG mediated pathways (e.g., in cardiac tissue). The invention further relates to pharmaceutical composition comprising the same and methods of treatment of cardiovascular disease and related disorders, e.g., congestive heart disease, atherosclerosis, myocardial infarction, and stroke.
