The Board of Trustees of the University of Arkansas;THE TEXAS A&M UNIVERSITY SYSTEM
发明人:
Walter Bottje,Billy Hargis,Luc Berghman,Young Min Kwon,Kimberly Cole,Mandy Cox,Sherryll Layton,Saeed El-Ashram,John Barta,Guillermo Tellez
申请号:
US16028599
公开号:
US20180333474A1
申请日:
2018.07.06
申请国别(地区):
US
年份:
2018
代理人:
摘要:
Vaccines comprising TRAP polypeptides and Salmonella enteritidis vectors comprising TRAP polypeptides are provided. The vaccines may also include a CD154 polypeptide capable of binding to CD40. Also provided are methods of enhancing an immune response against Apicomplexan parasites and methods of reducing morbidity associated with infection with Apicomplexan parasites.