KIM, BYUNG CHUL,김병철,LEE, CHANG HEE,이창희,JEON, WOO KWANG,전우광,CHOI, SHIN WOOK,최신욱
申请号：
KR1020120010355
公开号：
KR1020130089030A
申请日:
2012.02.01
申请国别(地区):
KR
年份:
2013
代理人:
摘要：
PURPOSE: A pharmaceutical composition for overcoming resistance to an anticancer agent is provided to suppress the activity of hemo oxygenase (HO) increased in cancer cells using methyl pheophorbide (MPP), thereby remarkably increasing apoptotic sensitivity in cancer cells with anticancer agent resistance. CONSTITUTION: A pharmaceutical composition for overcoming resistance to an anticancer agent contains MPP as an active ingredient. The anticancer agent is cisplatin. The effective concentration of MPP is 10 uM. A composition for suppressing HO contains MPP as an active ingredient.본 발명은 메틸 피오포바이드(Methyl pheophorbide)를 유효성분으로 포함하는 항암제 내성 극복용 의약 조성물, 헴 옥시데이즈 활성 저해용 조성물 및 그 방법 그리고 세포자멸사 촉진용 조성물 및 그 방법에 관한 것이다.
