DE FOUGEROLLES, Antonin,DIENER, John L.,HICKMAN, Emma,HINKLE, Gregory,MILSTEIN, Stuart,PULICHINO, Anne-Marie,SPRAGUE, Andrew
申请号:
AU2015221515
公开号:
AU2015221515A1
申请日:
2015.09.03
申请国别(地区):
AU
年份:
2015
代理人:
摘要:
#$%^&*AU2015221515A120150924.pdf#####Abstract The present disclosure relates to RNAi agents useful in methods of treating BetaENaC-related diseases such as cystic fibrosis, pseudohypoaldosteronism type I (PHA1), Liddles syndrome, hypertension, alkalosis, hypokalemia, and obesity-associated hypertension, using a therapeutically effective amount of a RNAi agent to Beta-ENaC.