Method for treating kidney disease with a SLIT2-binding extracellular domain of ROBO2

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专利权人:

BOSTON MEDICAL CENTER CORPORATION

发明人:

Weining Lu,Xueping Fan,David J. Salant

申请号：

US15399848

公开号：

US10358677B2

申请日:

2017.01.06

申请国别(地区):

US

年份:

2019

代理人:

摘要：

Provided herein are methods for the treatment of chronic kidney disease and proteinuria and for the diagnosis of chronic kidney disease and monitoring the effects of treatment on the progression of chronic kidney disease and proteinuria based on unexpected roles for the SLIT-ROBO signaling pathway in the regulation of podocyte F-actin cytoskeleton and foot process structure in the kidney.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/