University of Pittsburgh-of the Commonwealth System of Higher Education
发明人:
William E. Klunk,Chester A. Mathis, JR.
申请号：
US14050018
公开号：
US20140105820A1
申请日:
2013.10.09
申请国别(地区):
US
年份:
2014
代理人:
摘要：
The present method for determining the efficacy of therapy in the treatment of amyloidosis involves administering to a patient in need thereof a compound of formula (I) or Formula (II) or structures 1-45 and imaging the patient. After said imaging, at least one anti-amyloid agent is administered to said patient. Then, an effective amount of a compound of formula (I) or Formula (II) or structures 1-45 is administered to the patient and the patient is imaged again. Finally, baseline levels of amyloid deposition in the patient before treatment with the anti-amyloid agent are compared with levels of amyloid deposition in the patient following treatment with the anti-amyloid agent.
