Austin L. Gurney,Aaron Ken Sato,Fumiko Takada Axelrod,Timothy Charles Hoey,Sanjeev H. Satyal,Satyajit Sujit Kumar Mitra
申请号：
US13164191
公开号：
US08507442B2
申请日:
2011.06.20
申请国别(地区):
US
年份:
2013
代理人:
摘要：
Novel anti-cancer agents, including, but not limited to, antibodies, that bind to human frizzled receptors are provided. Novel epitopes within the human frizzled receptors which are suitable as targets for anti-cancer agents are also identified. Methods of using the agents or antibodies, such as methods of using the agents or antibodies to inhibit Wnt signaling and/or inhibit tumor growth are further provided.
