Acid Derivatives benzoazepin - Oxy acetic proliferator activated receptors as an agonist of LTA and used to increase high density lipoprotein cholesterol, low density lipoprotein, reduce cholesterol and reduce colesteol
KUO GEE HONG,YAN ZHANG,LAN SHEN,SONGFENG LU,KEITH T. DEMAREST,PATRICIA PELTON
申请号：
HN2008001559
公开号：
HN2008001559A
申请日:
2008.10.17
申请国别(地区):
HN
年份:
2012
代理人:
摘要：
The present Invention is directed to compounds of formula (i) useful as agonists of PPAR also described are Pharmaceutical compositions and Methods for treating one or more conditions including, but not limited to diabetes, nephropathy, neuropathy, retinopathy, polo ovary syndrome, Hypertension, ischemia, cerebral vascular accident, irritable bowel Disorder,Cataracts, inflammation, cardiovascular diseases, metabolic syndrome X, Mixed hyperlipidaemia, and hipohdl - cholesterol, atherosclerosis, obesity, and other Disorders related to Lipid Metabolism and complications of homoestasis Energy of same, using the compounds Encion.LA PRESENTE INVENCION ESTE DIRIGIDA A COMPUESTOS DE LA FORMULA (I) UTILES COMO AGONISTAS DE PPAR TAMBIEN SE DESCRIBEN COMPOSICIONES FARMACEUTICAS Y METODOS PARA TRATAR UNA O MAS CONDICIONES INCLUYENDO, PERO SIN LIMITARSE A DIABETES, NEFROPATIA, NEUROPATIA, RETINOPATIA, SINDROME DE OVARIO POLISTICO, HIPERTENSION, ISQUEMIA, ACCIDENTE VASCULAR CEREBRAL, TRASTORNO INTESTINAL IRRITABLE, INFLAMACION CATARATAS, ENFERMEDADES CARDIOVASCULARES, SINDROME METABOLICO X, HIPERLIPIDEMIA MIXTA, E HIPOHDL- COLESTEROLEMIA , ARTEROSCLEROSIS, OBESIDAD Y OTROS TRASTORNOS RELACIONADO CON EL METABOLISMO DE LIPIDOS Y COMPLICACIONES DE HOMOESTASIS DE ENERGIA DE LOS MISMOS, USANDO COMPUESTOS DE LA INVENCION.
