JOHANNES AEBI,ALFRED BINGGELI,LUKE GREEN,GUIDO HARTMANN,HANS P. MAERKI,PATRIZIO MATTEI,FABIENNE RICKLIN,OLIVIER ROCHE
申请号:
BRPI0813836
公开号:
BRPI0813836A2
申请日:
2008.07.17
申请国别(地区):
BR
年份:
2015
代理人:
摘要:
The invention is concerned with novel pyrazol derivatives of formula (I), wherein R1, R2, R3, R4, X and Y are as defined herein, as well as physiologically acceptable salts thereof. These compounds are antagonists of CCR-2 receptor and/or CCR-5 receptor and can be used as medicaments.