Ita Junkar,Rok Zaplotnik,Metka Bencina,Miran Mozetic
申请号：
US16594858
公开号：
US20200109469A1
申请日:
2019.10.07
申请国别(地区):
US
年份:
2020
代理人:
摘要：
The present invention improves the surface modification of NiTi alloys used for instance in medical devices through treatment with hydrogen particles in a suitable gaseous discharge and with oxygen atoms. The technique according to the present invention provides the formation of biocompatible solely titanium oxide layer thus preventing nickel to be present in the top surface layer. Furthermore this enables nanostructuring of the surface which depends on the treatment conditions. Devices made from NiTi alloys treated with the method according to the present invention have improved biocompatibility； platelets do not readily attach and activate on such surfaces and the thrombus formation rate is reduced in comparison with extensively used untreated NiTi alloys.
