Aspects of the present disclosure involve systems, methods, computer program products, and the like, for utilizing a series of images of a patients anatomy to determine a cut plane for use during a knee procedure. To determine a cut plane for use during a knee replacement procedure, the 2D images may be analyzed by a computer program to determine a femoral shaft axis reference line, a center of rotation of the knee, and the valley floor of the condyle notch. With these landmarks identified in the images, a cut plane through the femur for use during a TKA procedure may be determined. Further, the location of these features in the images may be determined by analyzing the gray scale value of one or more pixels around a selected point on the image. The pixel with the lowest gray scale value may then be assumed to be the edge of the cortical bone in the 2D image.
