Multi-functional laparoscopic surgical apparatuses (devices, systems) and applications (methods) for performing interventions in a subjects body. Exemplary embodiments are suitable for performing multiple different types of minimally invasive surgical procedures, such as tissue grasping, cutting, dissecting, fastening, and ligating, for example, via the same device. Exemplary apparatuses includes a tissue affecting device head that is reversibly convertible (transformable) between different tissue affecting configurations and modes (states) of operation, involving, for example, tissue dissecting, scissoring, and tissue grasping. Exemplary apparatuses and methods are implemented using a single, optionally, robotic, control unit. Also disclosed are exemplary embodiments of a surgical device including a longitudinal shaft enclosing a lumen having a cross section with a curved boundary, and a plurality of surgical instruments provided in the lumen, wherein at least two of the surgical instruments are packed according to a nested or/and concentric arrangement relative to the lumen curved boundary.