A guide catheter has an inlet orifice that allows blood to enter an interior passage of the catheter. A valve is positioned next to the inlet orifice that selectively opens and closes the inlet orifice. The catheter includes a dye passage that transports dye from a proximal end of the catheter to a dye outlet orifice. The dye passage may be formed in a unitary tubular member, a partitioned tubular member or in the clearances of a double-walled catheter. A valve may also be positioned next to the dye outlet orifices that selectively opens and closes the orifices. The valves are preferably kidney-shaped expandable bladders or pressure valves. A capillary tube connected to the expandable bladder functions to inflate and deflate the expandable bladder. The expandable bladders and capillary tubes are incorporated into the wall of the catheter.