Dolle, Roland E.,Le Bourdonnec, Bertrand,Ajello, Christopher W.,Gu, Minghua,Chu, Guo-Hua,Tuthill, Paul Anson,Leister, Lara K.,Zhou, Jean Q.
申请号:
AU2012216319
公开号:
AU2012216319A1
申请日:
2012.08.21
申请国别(地区):
AU
年份:
2012
代理人:
摘要:
#$%^&*AU2012216319A120120920.pdf#####Abstract Spirocyclic heterocyclic derivatives, pharmaceutical compositions containing these compounds, and methods for their pharmaceutical use are disclosed. In certain embodiments, the spirocyclic heterocyclic derivatives are ligands of the 6 opioid receptor and may be useful, inter alia, for treating and/or preventing pain, anxiety, gastrointestinal disorders, and other 6 opioid receptor-mediated conditions.