Salts of 2-fluoro-N-methyl-4-[7-(quinolin-6-yl-methyl)- imidazo[1,2-b][1,2,4]triazin-2-yl]benzamide and processes related to preparing the same

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专利权人:

Incyte Corporation

发明人:

Weng, Lingkai,Zhou, Jiacheng,Pan, Yongchun,Liu, Pingli,Qiao, Lei

申请号：

AU2009249154

公开号：

AU2009249154B9

申请日:

2009.05.20

申请国别(地区):

AU

年份:

2015

代理人:

摘要：

The present invention is directed to dihydrochloric acid and dibenzenesulfonic acid salts of the c-Met kinase inhibitor 2-fluoro-N-methyl-4-[7-(quinolin-6-ylmethyl)-imidazo[1,2-b][1,2,4]triazin-2-yl]benzamide, and pharmaceutical compositions thereof, useful in the treatment of cancer and other diseases related to the dysregulation of kinase pathways. The present invention further relates to processes and intermediates for preparing 2-fluoro-N-methyl-4-[7-(quinolin-6-ylmethyl)imidazo[1,2-b][1,2,4]triazin-2-yl]benzamide, and salts thereof.

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