Jeremiah F. Roeth,Charles C. Reed,Brandon Cuthbertson,Sunil Chada,William E. Fogler
申请号：
US16738015
公开号：
US20200239906A1
申请日:
2020.01.09
申请国别(地区):
US
年份:
2020
代理人:
摘要：
This invention relates to the field of therapeutics. Most specifically, the invention provides methods of generating conditionally expressing vectors for one or more immunomodulators under the control of a gene expression modulation system in the presence of activating ligand and uses for therapeutic purposes in animals. These vector may be provided to treat a variety of disorders, e.g., neoplastic disorders, through direct injection or through in vitro engineered cells, such as dendritic cells.
