Locked nucleic acid containing heteropolymers and related methods

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专利权人:

GOFF STEPHEN A

发明人:

GOFF STEPHEN A.

申请号：

US20060339459

公开号：

US2006117410(A1)

申请日:

2006.01.25

申请国别(地区):

美国

年份:

2006

代理人:

摘要：

The present invention relates to methods of replacing nucleotides in target nucleic acid sequences using DNA-LNA chimeras. The method of the present invention provides for replacing a first nucleotide in a target sequence by exposing the target sequence to a DNA-LNA heteropolymer and thereby replacing the first nucleotide with a second nucleotide. The invention also features the DNA-LNA chimeras themselves as well as methods of making them.

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中国工程科技知识中心

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http://www.ckcest.cn/home/