The Board of Trustees of the University of Arkansas
发明人:
Koonce, Nathan A.,Griffin, Robert
申请号：
AU2013274093
公开号：
AU2013274093A1
申请日:
2013.06.14
申请国别(地区):
AU
年份:
2014
代理人:
摘要：
Compositions and methods used in the non-invasive detection and/or treatment of hypoxic tissues in vivo are described. Compositions including microbubbles functionalized with one or more hypoxia targeting agents and one or more therapeutic compounds, methods of preparing the functionalized microbubbles, and methods of using the functionalized microbubbles for diagnostic and/or therapeutic applications are described, including a method for selectively determining the amount of vascular hypoxia occurring in a tissue.
