HONEYCUTT, Samuel E.,RUSSELL, Alan James,KRAMER, Henning Fritz
申请号：
USUS2013/042556
公开号：
WO2013/177478A3
申请日:
2013.05.24
申请国别(地区):
WO
年份:
2014
代理人:
摘要：
The present invention relates to methods of treating muscle injury, tendon damage, or a muscle degenerative disorder by administering inhibitors of prolyl 4-hydroxylase. The method comprises the administration of a prolyl 4-hydroxylase inhibitor to a patient. The inventors have shown that prolyl 4-hydroxlase inhibitors reduce muscle damage and preserve muscle function when administered prior to muscle damage in an in vivo assay for muscle function. Furthermore, the inventors have shown that when a prolyl 4-hydroxylase inhibitor is administered after muscle damage in the same assay, recovery of muscle function is enhanced.La présente invention concerne des méthodes de traitement dune lésion musculaire, dune lésion de tendon ou dun trouble de dégénérescence musculaire, par ladministration dinhibiteurs de la prolyl 4-hydroxylase.
