JIMENEZ, ANA I.,SESTO, ANGELA,ROMAN, JOSE P.,GASCON, IRENE,GONZALEZ DE BUITRAGO, GONZALO,JIMENEZ, MARIA CONCEPCION
申请号:
CA2594672
公开号:
CA2594672C
申请日:
2005.08.30
申请国别(地区):
CA
年份:
2014
代理人:
摘要:
Methods and compositions for the downregulation of P2X7 receptor expression oractivity are disclosed. Preferred compositions comprise siNA. The methods andcompositions are useful in the treatment of diseases characterised byincreased P2X7 receptor activity, such as neuronal degeneration, Alzheimer~sdisease, inflammatory diseases, and some cancers.