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Identification of Novel Disease States Using Viscoelastic Analysis in the Presence of an Thrombolytic Agent
专利权人:
The Regents of the University of Colorado; a body corporate
发明人:
Michael P. Chapman,Hunter B. Moore,Eduardo Gonzalez Barreda,Ernest E. Moore
申请号:
US15524095
公开号:
US20170336423A1
申请日:
2015.11.05
申请国别(地区):
US
年份:
2017
代理人:
摘要:
In some embodiments, the invention provides methods for detecting an aberrant fibrinolysis condition in a patient. The method includes subjecting a blood sample from the patient to a viscoelastic analysis in the presence of a known amount of a thrombolytic agent, to obtain a coagulation characteristic value of the patient; and comparing the coagulation characteristic value of the patient to a coagulation characteristic value of a healthy individual, the coagulation characteristic value of the healthy individual obtained by subjecting a blood sample from a healthy individual to the viscoelastic analysis in the presence of the known amount of the thrombolytic agent, wherein a difference in the coagulation characteristic value of the patient as compared to the coagulation characteristic value of the healthy individual identifies the patent as having aberrant fibrinolysis. In some embodiments, the invention also provides a container adapted for detecting an aberrant fibrinolysis condition in a blood sample using viscoelastic analysis comprising an interior having a coating comprising a thrombolytic agent.
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