#$%^&*AU2020202839A120200521.pdf#####ABSTRACT Pharmaceutical and veterinary compositions for oral administration comprising a therapeutically effective amount of at least one coxib together with a therapeutically 5 effective amount of pentosan polysulfate or a pharmaceutically acceptable salt thereof are described. The compositions have application for the prophylaxis or treatment of pain and/or inflammation. There is also described a pharmaceutical or veterinary composition comprising a therapeutically effective amount of at least one coxib. The compositions in at least some forms may be lactose free and/or provided in a non10 gelatin capsule. Further, there are provided methods for administration of a therapeutically effective amount of at least one coxib in combination with pentosan polysulfate or a pharmaceutically acceptable salt thereof for the prophylaxis or treatment of pain and/or inflammation.1/2 FIGURE 1 0 OR OR 0 OR 0 OR 0 OR 0 OR 0 OR 0 OR OOR Q,0 OR OR OR OR OR OR R = SO 3Na 0ORO MeO a OR N FIGURE 2 Hand OA Treatment Comparisons 150 Pentacoxib * Celecoxib Group (n = 5) Group (n =4) S 100 E O 50 1 50 -- 0 -. --50 Cii0 Para er Clinical Parameter
