#$%^&*AU2020203212A120200611.pdf#####Abstract Provided herein are methods and compositions for stabilization of active agents. The active agents are distributed, mixed or embedded in a silk fibroin matrix, thereby retaining the bioactivity of the active agents upon storage and/or transportation. In some embodiments, the storage-stable vaccine-silk compositions are also provided herein.WO 2012/145739 PCT/US2012/034643 12/22 I I AMI ivni % M1dICI3 CCIA o - --- -----(AON31Od IVOOISIH (%A33IOd 1VOWIS]N Cl T7" l IrIPTT PT ClT T7 T7IP T-')T Tr T