THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM
发明人:
FROLOV, ILYA,FROLOVA, ELENA,MASON, PETER W.
申请号：
CA2643819
公开号：
CA2643819C
申请日:
2007.02.27
申请国别(地区):
CA
年份:
2018
代理人:
摘要：
The present invention discloses a replication-deficient pseudoinfective virus belonging to the Flaviviridae family that lack the capsid gene, where the replication- deficient pseudoinfective virus propagates only in cells expressing the capsid or capsid, prM and envelope protein of the flavivirus. The present also discloses the method of producing such viruses on a large scale and the use of these pseudoinfective viruses as vaccines for preventing diseases caused by infections of humans or animals by the viruses belonging to this family.
