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Antiinflammatory and antitumor 2-oxothiazoles and 2-oxothiophenes compounds
专利权人:
AVEXXIN AS
发明人:
JOHANSEN, Berit,SANDBERG, Marcel,AUKRUST, Inger-Reidun,KOKOTOS, George,BARBAYIANNI, Efrosini
申请号:
AU2018208695
公开号:
AU2018208695A1
申请日:
2018.07.26
申请国别(地区):
AU
年份:
2018
代理人:
摘要:
#$%^&*AU2018208695A120180809.pdf#####Abstract 0 (R1 )n R4 A compound of formula (I) R2 () wherein X is 0, C=O or S; Y is N or CH; R 2 and R4 are each independently H, -(CH 2)pCOOH, -(CH 2)pCON(R) 2 or -(CH 2)pCOOCI-6alkyl; or R2 and R4 together form a 6-membered phenyl ring fused to the five membered ring; each R1 is independently selected from H, halo (e.g. fluoro or chloro), C6-ioaryl, C7-12arylalkyl, C2-12 alkenyl; OCI- 12 alkyl, OC 2-12 alkenyl or a CI- 12 alkyl group; each R5 is H or C1- 6 alkyl; each p is 0 to 3; n is 1 to 4; or a salt, ester, solvate, N-oxide, or prodrug thereof, e.g. a salt thereof.
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