CID-NUNEZ, JOSE MARIA,TRABANCO-SUAREZ, ANDRES AVELINO,VEGA RAMIRO, JUAN ANTONIO,OEHLRICH, DANIEL,TRESADERN, GARY JOHN,MACDONALD, GREGOR JAMES
申请号：
CA2815002
公开号：
CA2815002C
申请日:
2011.11.08
申请国别(地区):
CA
年份:
2019
代理人:
摘要：
The present invention relates to triazolo[4,3-a]pyridine derivatives ofFormula (I). The compounds arepositive allosteric modulators of the metabotropic glutamate receptor subtype2 ("mGluR2"), which areuseful for the treatment or prevention of neurological and psychiatricdisorders associated with glutamatedysfunction and diseases in which the mGluR2 subtype of metabotropic receptorsis involved. Theinvention is also directed to pharmaceutical compositions comprising suchcompounds, to processes toprepare such compounds and compositions, and to the use of such compounds forthe prevention ortreatment of neurological and psychiatric disorders and diseases in whichmGluR2 is involved.(see formula I)
