Novel Spiro and Cyclic Bis-Benzylidene Proteasome Inhibitor for the Treatment of Cancer, Diabetes and Neurological Disorders
- 专利权人:
- UP THERAPEUTICS; INC.
- 发明人:
- Yung-Nien Chang
- 申请号：
- US16481562
- 公开号：
- US20190365726A1
- 申请日:
- 2018.01.30
- 申请国别(地区):
- US
- 年份:
- 2019
- 代理人:
- 摘要：
- Described herein are spiro and cyclic bis-benzylidine proteasome inhibitors, which inhibit the proteasome function through either ubiquitin receptor ADRM1/RPN13 or proteasome DUB enzymes (USP14, UCH37 and RPN11), and which can be used for the treatment of cancers/diabetes/neurological disorders.
- 来源网站：
- 中国工程科技知识中心
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