Yunfeng Fang;Hengyuan Lang;Olga M. Fryszman;Jiong Lan;Edcon Chang
发明人:
Olga M. Fryszman,Hengyuan Lang,Jiong Lan,Edcon Chang,Yunfeng Fang
申请号：
US13530919
公开号：
US08410160B2
申请日:
2012.06.22
申请国别(地区):
US
年份:
2013
代理人:
摘要：
Provided are 5-membered heterocycle-based p38 kinase inhibitors. Further provided are pyrazole and imidazole-based p38 kinase, including p38α, and p38β kinase, inhibitors. Pharmaceutical compositions containing the compounds are also provided. Methods of use of the compounds and compositions are also provided, including methods of treatment, prevention, or amelioration of one or more symptoms of p38 kinase mediated diseases and disorders, including, but not limited to, inflammatory diseases and disorders.
