Brooke Emerling,Atsuo Sasaki,Lewis C. Cantley,Jonathan Hurov
申请号:
US13985462
公开号:
US09493813B2
申请日:
2012.01.13
申请国别(地区):
US
年份:
2016
代理人:
摘要:
The invention features methods for identifying compounds that modulate the activity of phosphatidylinositol 5-phosphate 4-kinase (PI5P4K). Inhibitors of PI5P4K can be used in, for example, the treatment or prevention of cell proliferation disorders (e.g., the prevention of tumor cell growth in p53 mutated cancers).