Michael Joseph Luzzio,Julien Papillon,Michael Scott Visser
申请号:
US15237880
公开号:
US09845309B2
申请日:
2016.08.16
申请国别(地区):
US
年份:
2017
代理人:
摘要:
PKC inhibitors are disclosed. The PKC inhibitors are useful for treating PKC associated diseases, including certain cancers. The PKC inhibitors have improved efficacy at lower dosage amounts to achieve tumor regression, improved potency, PK profile, absorption, gastrointestinal tolerance and kinase selectivity.