KORNEEVA OLGA SERGEEVNA,Корнеева Ольга Сергеевна,KIRJANOVA SVETLANA VLADIMIROVNA,Кирьянова Светлана Владимировна,TOLKACHEVA ANNA ALEKSANDROVNA,Толкачева Анна Александровна,ANOKHINA EKATERINA PETROVNA
申请号:
RU2013143212
公开号:
RU2571274C2
申请日:
2013.09.24
申请国别(地区):
RU
年份:
2015
代理人:
摘要:
FIELD: medicine, pharmaceutics.SUBSTANCE: invention refers to pharmaceutical industry, namely to a method for producing fucose and fucose-containing hydrolysates from brown algae. The method for producing fucose and fucose-containing hydrolysates from brown algae consists in the fact that ground brown alga of the genus Fucus is filled with ethanol, extracted the extract is separated the processed alga is extracted with hydrochloric acid solution the extract is concentrated, neutralised, boiled off to produce a concentrate containing polysaccharide-1, from which fucoidan (F1) is deposited after F1 is separated, the processed alga is twice extracted with hot water the extracts are combined and concentrated the produced concentrate is boiled off, and polysaccharide-2 is produced ph is reduced to 2.0-2.5 precipitated polymannuronic acid is separated by centrifugation the supernatant is neutralised, and fucoidan (F2) is deposited with ethanol the deposit is washed in ethanol and dried both fractions F1 and F2 are combined and dissolved in distilled water the fucoidan solution is subject to dialysis thereafter, fucoidan is deposited with two amounts of ethanol the deposit is washed in ethanol twice, dried the dried fucoidan is dissolved in distilled water and subject to enzymatic hydrolysis produced fucose is dried the fucose-containing hydrolysates are produced by dissolving fucoidan in distilled water and subject to enzymatic hydrolysis the produced fucose-containing hydrolysates are dried in certain environment.EFFECT: method enables manufacturing the high-yield end product from available raw materials.2 exИзобретение относится к фармацевтической промышленности, а именно к способу получения фукозы и фукозосодержащих гидролизатов из бурых водорослей. Способ получения фукозы и фукозосодержащих гидролизатов из бурых водорослей заключается в том, что измельченную бурую водоросль рода Fucus заливают этанолом, экстрагируют, экстракт отделяют, затем обработанную водоросль э