Glenn Francis Browning,Philip Francis Markham,Chi-Wen Tseng
申请号:
US13202534
公开号:
US20120045475A1
申请日:
2010.02.17
申请国别(地区):
US
年份:
2012
代理人:
摘要:
The present invention relates to a bacterium attenuated by a mutation in at least one ABC transporter gene wherein the mutation renders the corresponding ABC transporter protein non-functional and wherein the attenuated bacterium persists in a subject.