Medical dressings are disclosed that include multiple exposed pressure sensitive adhesives. One of the pressure sensitive adhesives includes a bioactive agent and is substantially contact transparent. In some embodiments, all of the adhesives are substantially contact transparent. Also provided are methods of manufacturing the medical dressings. By providing multiple exposed pressure sensitive adhesives, the pressure sensitive adhesive formulations can be varied to provide desired properties in different areas of the dressing. A pressure sensitive adhesive that exhibits relatively high lack to skin may be provided around the periphery of the dressing while a pressure sensitive adhesive incorporating a bioactive agent is provided in the center of the dressing Alternatively, a higher tack pressure sensitive adhesive may be provided at two opposing sides of the dressing with a bioactive adhesive located in between the opposing portions of higher tack adhesive. The present invention also provides methods of transferring adhesives using a mask such that the adhesive is transferred to selected areas of a receiving surface the mask may he provided in the form of a liner including a plurality of voids formed therein.
