PROCÉDÉS DE TRAITEMENT DE L'HYPERURICÉMIE CHEZ DES PATIENTS ATTEINTS DE GOUTTE, AU MOYEN D'HALOFÉNATE OU D'ACIDE HALOFÉNIQUE ET D'UN SECOND AGENT DE RÉDUCTION D'URATE
ROBERTS, BRIAN K.,SAHA, GOPAL CHANDRA,LAVAN, BRIAN EDWARD,MCWHERTER, CHARLES A.
申请号:
EP11875114
公开号:
EP2773336A4
申请日:
2011.11.04
申请国别(地区):
EP
年份:
2015
代理人:
摘要:
Disclosed herein are pharmaceutical compositions, methods and kits for lowering the serum uric acid level of a subject and for the treatment of a condition associated with elevated serum uric acid levels comprising administering a composition comprising a first urate-lowering agent and a second urate-lowering agent. In some aspects the first urate-lowering agent is (-)- halofenate, (-)- halofenic acid, or a pharmaceutically acceptable salts thereof. In some aspects the second urate-lowering agent is an inhibitor of uric acid production, a uricosuric agent, a uricase, or a pharmaceutically acceptable salt thereof.