Blood platelet is not reduced and does not reduce the CD47 antibody and its application method of erythrocyte

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专利权人:

INHIBRX, INC.;印希彼有限公司

发明人:

B．埃克尔曼,B．埃克爾曼,J．蒂莫,A．拉扎伊,Q．德福罗,Q．德福羅,K．琼斯,K．瓊斯,M．拉普

申请号：

MOJ003573

公开号：

MOJ003573B

申请日:

2019.02.01

申请国别(地区):

MO

年份:

2019

代理人:

摘要：

The present invention relates generally to the monoclonal antibodies of identification CD47, relate more specifically to not cause the cell agglutination of significant level, erythrocyte to reduce, the CD47 antibody of anaemia and/or decrease of platelet, it is related to generating the method for these antibody, and is related to the method for using these monoclonal antibodies as therapeutic agent.本發明通常涉及識別CD47的單克隆抗體，更具體地涉及不導致顯著水平的細胞凝集、血紅細胞減少、貧血和／或血小板减少的CD47抗體，涉及生成這些抗體的方法，以及涉及使用這些單克隆抗體作爲治療劑的方法。

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/