PURPOSE: A composition containing red ginseng extract and soybean fermentation extract is provided to treat and prevent hyuperlipidemia and arteriosclerosis. CONSTITUTION: A pharmaceutical composition for preventing or treating hyperlipidemia and arteriosclerosis contains acid hydrolzed red ginseng extract with enhanced ginsenoside Rg3 content and soybean fermentation extract. The soybean fermentation extract is prepared by adding natto or natto bacteria to sterilized soybeans, shaking for 20-30 hours, filtering, and concentrating the supernatant. A health functional food composition for preventing or treating hyperlipidemia and arteriosclerosis contains the red ginseng extract and soybean fermentation extract. [Reference numerals] (AA) Control group； (BB) Hyperlipidemia development group； (CC) Oral administration group of red ginseng extract after hyperlipidemia development； (DD) Administration group of red ginseng extract + soybean fermented extract after hyperlipidemia development； (EE) Administration group of soybean fermented extract after hyperlipidemia development； (FF) Total cholesterol(mg/d)본 발명은 홍삼 추출물과 대두 발효추출물을 포함하는 항고지혈증 및 항동맥경화 조성물 및 그 제조방법에 관한 것으로, 좀더 자세히는 진세노사이드 Rg3의 함량을 높이기 위해 산 가수분해를 통해 얻은 홍삼 추출물과 바실러스속 균주를 이용하여 발효한 대두 추출물을 혼합하여 고지혈증 및 동맥경화 개선 및 예방의 효능이 있는 조성물에 관한 것이다.
