PATRICK GENTY,CHRISTOPHE HERMELIN,JEAN MANUEL PEAN
申请号：
FR1200322
公开号：
FR2986431B1
申请日:
2012.02.03
申请国别(地区):
FR
年份:
2017
代理人:
摘要：
Composition for prolonged release of trimetazidine, comprises an inner phase comprising trimetazidine and an outer layer comprising a retardant and an antiagglomerant. An independent claim is included for preparing the composition comprising coating the neutral cores with trimetazidine and the binder to form minigranules, coating the minigranules with the retardant, the plasticizer and the antiagglomerant, and filling the coated minigranules into capsules, optionally in the presence of a lubricant. ACTIVITY : Antianginal； Ophthalmological； Auditory. MECHANISM OF ACTION : None given.
