作為免疫調節劑的三並環化合物农业专利-农业学术服务平台

专利权人:: MEDSHINE DISCOVERY INC.;CHIA TAI TIANQING PHARMACEUTICAL GROUP CO., LTD.

发明人:: LIU, SHILAN,刘世岚,劉世嵐,WANG, DAHAI,王大海,LIANG, GUIBAI,梁贵柏,梁貴柏,HU, GUOPING,胡国平,胡國平,LI, JIAN,黎　健,CHEN, SHUHUI,陈　曙辉,陳　曙輝,黎健,陈曙辉,陳曙輝

摘要：: The present application relates to the compound of formula (I), or a pharmaceutically acceptable salt and pharmaceutical composition thereof, the compound of formula (I) or the pharmaceutically acceptable salt and pharmaceutical composition thereof having indole-2, 3-dioxygenase (IDO) inhibitory activity, and being able to treat immunosuppressive diseases mediated by indole-2, 3-dioxygenase (IDO), such as infectious diseases or cancer.本發明涉及通式I和通式II的化合物或其藥學上可接受的鹽及其藥物組合物，該通式I和通式II的化合物或其藥學上可接受的鹽及其藥物組合物具有吲哚2,3-雙加氧酶(IDO)抑制活性，能治療由吲哚2,3-雙加氧酶(IDO)介導的免疫抑制疾病，如傳染性疾病或癌症。