BALDWIN, JOHN J.,CLAREMON, DAVID A.,TICE, COLIN,CACATIAN, SALVACION,DILLARD, LAWRENCE W.,ISHCHENKO, ALEXEY V.,YUAN, JING,XU, ZHENRONG,MCGEEHAN, GERARD,SIMPSON, ROBERT D.,SINGH, SURESH B.,ZHAO, WEI,FLA
申请号:
CA2628952
公开号:
CA2628952C
申请日:
2006.11.13
申请国别(地区):
CA
年份:
2014
代理人:
摘要:
The present invention is directed to aspartic protease inhibitors. Certainaspartic protease inhibitors of the invention can be represented by thefollowing structural formula or a pharmaceutically acceptable salt thereof.The present invention is also directed to pharmaceutical compositionscomprising the disclosed aspartic protease inhibitors. The present inventionis further directed to methods of antagonizing one or more aspartic proteasesin a subject in need thereof, and methods for treating an aspartic proteasemediated disorder in a subject using the disclosed aspartic proteaseinhibitors.