POULTON LYNN DOROTHY,CLARKE ADAM,POW ANDREW JAMES,TAMVAKIS DEBRA,KOPSIDAS GEORGE,DOYLE ANTHONY GERARD,JENNINGS PHILIP ANTHONY,POLLARD MATTHEW
申请号:
ZA201401843
公开号:
ZA201401843B
申请日:
2014.03.13
申请国别(地区):
ZA
年份:
2015
代理人:
摘要:
The present disclosure provides TNF-like ligand 1a (TL1a)-binding proteins comprising an antigen binding domain of an antibody which binds specifically to TL1a and inhibits interaction of TL1a and Death Receptor 3 (DR3) and which does not inhibit the interaction of TL1a and Decoy Receptor 3 (DcR3). The present disclosure also provides uses of the TL1a-binding proteins.