The present invention provides comprising the beverage and pharmaceutical composition according to the deuterated ethyl alcohol of formula 1, and provide the method for its manufacture and use. It is expected that the related side effect of some consumption with ethyl alcohol of composition for improved of the invention, such as it is still drank after a night and flush.本發明提供了包含根據式1的氘代乙醇的飲料和藥物組合物,並且提供了其製造和使用的方法。預期本發明的組合物改善一些與乙醇的消耗有關的副作用,諸如宿醉和面部潮紅。