Philip Cohen,Kristopher Clark,Hwan Geun Choi,Nathanael Gray
申请号:
US14385077
公开号:
US09670165B2
申请日:
2013.03.13
申请国别(地区):
US
年份:
2017
代理人:
摘要:
The present invention relates to the discovery that salt inducible kinases (SIKs) suppress the formation of anti-inflammatory molecules such as IL-10, which are important for the resolution of inflammation and identifies SIK inhibitors that may be used to treat disorders associated with undesirable inflammation, such as inflammatory bowel disease and/or autoimmune disorders.