Carmen Almansa-Rosales,Monica Garcia Lopez,Ana-Maria Caamano-Moure
申请号:
US15527909
公开号:
US10407428B2
申请日:
2015.11.20
申请国别(地区):
US
年份:
2019
代理人:
摘要:
The present invention relates to spiro-isoquinoline-1,4′;-piperidine compounds having dual pharmacological activity towards both the sigma (σ) receptor and the μ-opiod receptor, to processes of preparation of such compounds, to pharmaceutical compositions comprising them, and to their use in therapy, in particular for the treatment of pain.