Niels P. Ryde,Peter Snyder,Wei Liu,David M. Slifer
申请号：
US15130396
公开号：
US09974748B2
申请日:
2016.04.15
申请国别(地区):
US
年份:
2018
代理人:
摘要：
This invention is directed to reduction of flake-like aggregation in nanoparticulate compositions. Also encompassed by the invention are compositions comprising a nanoparticulate active agent, at least one surface stabilizer and a flake-like aggregation reducing agent, such as a buffer and a sugar. The nanoparticulate active agent compositions comprise particles of the active agent having an effective average particle size of less than about 2000 nm.
