Volkmar Guenzler-Pukall;Michael P. Arend;Qingjian Wang;Alex Melekhov;Thomas B. Neff;Lee A. Flippin
发明人:
Volkmar Guenzler-Pukall,Thomas B. Neff,Qingjian Wang,Michael P. Arend,Lee A. Flippin,Alex Melekhov
申请号:
US12928119
公开号:
US08466172B2
申请日:
2010.12.02
申请国别(地区):
US
年份:
2013
代理人:
摘要:
The present invention relates to methods of stabilizing the alpha subunit of hypoxia inducible factor (HIF). The invention further relates to methods of preventing, pretreating, or treating conditions associated with HIF, including ischemic and hypoxic conditions. Compounds for use in these methods are also provided.