The present disclosure is directed to crystalline forms of oxymorphone hydrochloride and compositions comprising any of the crystalline forms of oxymorphone hydrochloride. Also provided are processes for the preparation of crystalline forms of oxymorphone hydrochloride.Linvention concerne des formes cristallines de chlorhydrate doxymorphone ainsi que des compositions contenant une de ces formes cristallines. Linvention concerne également des procédés de préparation de formes cristallines de chlorhydrate doxymorphone.