The Johns Hopkins University;The University of North Carolina at Chapel Hill
发明人:
Samuel Lai,Ying-Ying Wang,Arthi Kannan,Kennetta Nunn,Durai Babu Subramani,Richard Cone
申请号:
US14438511
公开号:
US10100102B2
申请日:
2013.10.29
申请国别(地区):
US
年份:
2018
代理人:
摘要:
The presently-disclosed subject matter relates to antibodies, compositions, and methods for inhibiting and treating pathogen infection and providing contraception. In particular, the presently-disclosed subject matter relates to inhibiting and treating pathogen infection and providing contraception in a subject using compositions and antibodies capable of trapping pathogens or sperm in mucus, thereby inhibiting transport of pathogens or sperm across mucus secretions. The subject matter further relates to methods for monitoring the effectiveness of vaccines by detecting antibodies capable of trapping pathogens in mucus.