IFAK assemblies may include an outer shell having a first outer shell end. a second outer shell end, an outer shell interior extending between the first outer shell end and the second outer shell end, a first shell opening at the first outer shell end and a second shell opening at the second outer shell end. An interior sleeve may be removably deployed in the outer shell interior of the outer shell. The interior sleeve may be selectively removable from a selected one of the first shell opening and the second shell opening. A plurality of first aid items may be carried by the interior sleeve. A left tourniquet sleeve may be carried by a first side of the outer shell. The left tourniquet sleeve may have a left sleeve interior configured to contain at least one left tourniquet and a left tourniquet retrieval opening corresponding in position to the first outer shell end of the outer shell, At least one left sleeve compression hand may be provided in the left tourniquet sleeve. A right tourniquet, sleeve may be carried by a second side of the outer shell opposite the first side. the right tourniquet sleeve may have a right sleeve interior configured to contain at least one right tourniquet and a right tourniquet retrieval opening corresponding in position to the second outer shell end of the outer shell. At least one right sleeve compression hand may be provided in the right tourniquet sleeve.