The present disclosure relates to polypeptides (also referred to herein as CXCR4 binding molecules or polypeptides) that are directed against the G coupled protein receptor CXCR4 also known as Fusin or CD184. The invention also relates to nucleic acids encoding such polypeptides to methods for preparing such polypeptide to compositions and in particular to pharmaceutical compositions that comprise such polypeptides and to uses of such polypeptides for therapeutic or diagnostic purposes.
